Newsletter registration

By using our website, you are agreeing to cookies being stored and Google Analytics being used on your device in order to offer the best possible service. You can find more information on thishere.
Austria.
Where Your Profits Grow Sky High.

Bacteria compensate for fitness loss through antimicrobial resistance

Photo: APA (Fohringer) © Photo: APA (Fohringer)

The antibiotic Rifampicin inhibits an enzyme in bacteria cells with which read the genetic material in order to build a model for proteins (RNA polymerase). If this enzyme is changed, it cannot be attacked by antibiotics, but does not function as efficiently any more, and the microbes’ “fitness” deteriorates.

In the case of Pseudomonas-aeruginosa bacteria, the researchers discovered that these pathogens slowly but surely compensate for a fitness loss by means of a Rifampicin resistance. They can simply compensate for small handicaps by ensuring that other cellular functions become even more effective. The overall fitness level once again resembles the fitness of the non-resistant bacteria.

However, if the fitness loss is considerable as a consequence of the resistance to the antibiotics, they process no longer works. In this case the bacteria have to completely restore the function of the enzymes by detours. The scientists reported that this is up to 10,000 times more difficult (less probable). The study is designed to contribute to an understanding of the dynamic processes involved in a spreading of antimicrobial resistance, especially in a clinical environment. 

Share on Facebook Share on Facebook Share on Twitter Share on Twitter Share on Linkedin Share on Linkedin

Testimonials

Events

Meet us at events, seminars and trade shows - worldwide.

  • Meet us in Moscow

    23. - 26.04.2019, Moscow

  • Meet us @ Pioneers

    09. - 10.05.2019, Vienna

Austria Map

Find the perfect location for your company

We are lucky to benefit from a lot of reserach incentives here in Austria. We are very proud to be here as Austria is an ideal location for research.

TachoEASY Austria

Logo
More testimonials

news from the business location Austria

Maximize profitability with Vertec

After establishing a subsidiary in Austria in the beginning of 2019, the Swiss software specialist Vertec now operates in the entire DACH region.

Blockchain Technologies: Austria’s Contribution in the Global Race

An international race focusing on the blockchain technology underlying cryptocurrency is currently taking place, not least due to the Bitcoin hype in 2017. Asia and in particular China are a step ahead at present, whereas the USA is somewhat behind. The blockchain industry is still in an embryonic state in large parts of Europe. Find out here why there is still hope and what role Austria is playing.

More news All blog posts