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Cancer formation: Clumps of protein inhibit anti-carcinogenic network

Photo: APA (Fohringer) © APA (Fohringer)

These new findings about the derailment of cancer cells supply several reference points for carrying out further research on treating cancer. Tobias Madl of the Institute for Molecular Biology and Biochemistry at the Medical University of Graz and his working group have elucidated the structure of protein clumps on behalf of the research team at the University Medical Center Utrecht, the University of Utrecht and Francis Crick Institute in London. The results of the entire study were published in the latest issue of the scientific journal "Nature Structural and Molecular Biology".

Service: Anvarjan Z., Nojima H., van Kappel E., Madl T. et al: "Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network", Nature Structural and Molecular Biology, März 2016, http://dx.doi.org/10.1038/nsmb.3191

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