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Insulin nasal spray against loss of smell

Scientists led by Veronika Schöpf of the University Department of Radiology and Nuclear Medicine based their findings in the pilot study published in the scientific journal “Rhinology” from observations made recently in connection with brand functions, the sense of smell and the hormone insulin, which is decisive in ensuring the glucose balance in the body.

In the study, the scientists attempt to influence the loss of smell. Five patients with such symptoms following infections were given an insulin nasal spray (40 international units), and five comparable patients were given a placebo. The sense of smell was tested beforehand and afterwards. „In applying the insulin, the patients showed an immediate improvement with respect to their sense of smell and the ability to assess the intensity of smells”, the scientists said in commenting on the results. In addition, they observed an improvement in the ability of test persons with high body weight to recognize smells.

The results illustrate the apparent connection between the insulin level in the brain and the person’s loss of her or his ability to smell. Potentially this could be used in developing quickly effective therapies in the case of an acute loss of smell. 

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