One of the reasons is that over the last ten years, about 10,000 patients have been treated within the context of close to 500 clinical studies. These studies enabled the patients to receive the most modern therapies and drugs. The Cancer Cluster Salzburg (CCS) has been conducting research on the interaction between tumor cells with directly neighboring cells. “Therapies oriented against the tumor milieu are increasingly considered as effective approaches. For this reason, this research focus has forward-looking significance”, Greil states.
Examinations of stem cell properties of leukemia cells are also promising. Signal transmission between these and the tumor environment could open up new therapeutic approaches. For this purpose, the researchers in Salzburg have access to the world’s largest database of patients treated with hypomethylating substances and related leukemia samples. The “Smart Specialization Center” dealing with the personalized treatment of cancer is now being restructured.