This "atypical" virus, which the scientists named "MKPV" (for Mouse Kidney Parvovirus), belongs to the family of parvoviruses. The results of the study have now been published in the leading international scientific journal "Cell".
The researchers developed a new model for studying viral kidney diseases, renal fibrosis and chronic renal failure. In contrast to previously used models, which are primarily based on surgical interventions or the administration of toxic substances, MKPV infection is a natural model, very similar to the chronic course of renal failure in humans. This model can now be used to test new drugs to combat renal fibrosis and chronic kidney failure. It will also be possible to discover new biomarkers for these diseases and develop them for clinical application.